NLRP3

(redirected from FCAS)
Also found in: Acronyms.

NLRP3

A gene located on chromosome 1q44 that encodes a pyrin-like protein that interacts with the apoptosis-associated speck-like protein PYCARD/ASC. NLRP3 has a caspase recruitment domain, and belongs to the NALP3 inflammasome complex; it plays a role in regulating inflammation and apoptosis.
 
Molecular pathology
NLRP3 mutations are associated with chronic infantile neurological cutaneous and articular (CINCA) syndrome, familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome and neonatal-onset multisystem inflammatory disease (NOMID).
References in periodicals archive ?
In addition, the integration of Latens FCAS with the Amino set-top boxes and PVR's, widens the choice for all IPTV operators to offer advanced services in order to better compete in the market place.
The FCAS approach to security is unique in many ways, with pre-emption of piracy a particular advantage over other CA solutions.
ConGen Jamoralin and Assistant Attorney General Woody Pengele inducted the FCAS officers.
On August 28, Consul General Jamoralin paid a courtesy call on Governor Lolo Letalu Matalasi Moliga, accompanied by officers of FCAS led by Reynaldo Sellos, President.
Hurricane Model," said David Lalonde, FCAS, FCIA, MAAA, senior vice president at AIR Worldwide.
Sanjay Godhwani, FCAS, MAAA EVP and property division executive, Lexington Insurance Company
Sanjay Godhwani, FCAS, MAAA, EVP and property division executive, Lexington Insurance Company
FCAS countries are generally characterized by political instability, weak governance and institutional capacity, economic and social insecurity, and greater vulnerability to the effects of climate change.
Receiving this inaugural award is a great honor for AIR in that it recognizes the hard work and exceptional customer service provided by our cross-functional team of scientists, analysts and consultants," said David Lalonde, FCAS, FCIA, MAAA, senior vice president at AIR Worldwide.
Kliethermes, FCAS, MAAA, CPCU, to the position of senior vice president, risk services.