FANCD2

FANCD2

A gene on chromosome 3p26 that encodes a protein of the Fanconi anaemia complementation group (here, complementation group D2), which co-locates with other proteins—e.g., BRCA1 and BRCA2—and is involved in homology-directed DNA repair.
References in periodicals archive ?
Scientists had shown previously that DNA repair was much less efficient when FANCI and FANCD2 lack the single ubiquitin.
Researchers have shown exposure to cigarette smoke slows production of a protein called FANCD2 in lung cells.
A total of eight complementation groups have been identified, and six genes (FANCA, FANCC, FANCD2, FANCE, FANGF, FANCG) have been cloned so far (Tamary et al.