BPTF

(redirected from FAC1)

BPTF

A gene on chromosome 17q24.3 that encodes a histone-binding component of nucleosome-remodelling factor (NURF), a protein complex which catalyses ATP-dependent nucleosome sliding and facilitates transcription.

Molecular pathology
High levels of FAC1/BPTF may be found in foetal brain and in patients with neurodegenerative diseases (e.g., Alzheimer’s disease).
References in periodicals archive ?
no 3 15 4 15 9 1 2 3 4 5 FAC1 4,33 3,88 3,97 4,5 4,61 FAC2 3,89 3,28 3,75 4,53 4,78 FAC3 4,5 4,46 2,25 4,77 4,72 FAC4 4,67 3,66 4,44 4,6 4,61 FAC5 4,83 3,76 4,25 4,67 4,5 FAC6 2,67 2,66 2,69 1,87 4,33 FAC7 1,67 4,04 3,75 4,73 4,44 Source: Elaborated by the authors.
Where: FAC1 = Reliability; FAC2 = Access; FAC3 = Ease of use; FAC4 = Personalization; FAC5 = Credibility; FAC6 = Security; fac1 = Security; fac2 = Responsiveness; fac3 = Ease of Use; fac4 = Availability; fac5 = Reliability; fac6 = Personalization; fac7 = Access; Edu = Education Levels; [SQ.
Breast Hormone 30 -1 Breast FAC1 50-80 -1 Ovarian Taxane-platinum 60 -2 Testicular Platinum regime 80 -3 Colorectal 5FU + LV 20 -4 (a) FAC, fluorouracil, doxorubicin, and cyclophosphamide; 5FU + LV, 5-fluorouracil + leucovorin.