BPTF

(redirected from FAC1)

BPTF

A gene on chromosome 17q24.3 that encodes a histone-binding component of nucleosome-remodelling factor (NURF), a protein complex which catalyses ATP-dependent nucleosome sliding and facilitates transcription.

Molecular pathology
High levels of FAC1/BPTF may be found in foetal brain and in patients with neurodegenerative diseases (e.g., Alzheimer’s disease).
References in periodicals archive ?
Where: FAC1 = Reliability; FAC2 = Access; FAC3 = Ease of use; FAC4 = Personalization; FAC5 = Credibility; FAC6 = Security; fac1 = Security; fac2 = Responsiveness; fac3 = Ease of Use; fac4 = Availability; fac5 = Reliability; fac6 = Personalization; fac7 = Access; Edu = Education Levels; [SQ.
Breast Hormone 30 -1 Breast FAC1 50-80 -1 Ovarian Taxane-platinum 60 -2 Testicular Platinum regime 80 -3 Colorectal 5FU + LV 20 -4 (a) FAC, fluorouracil, doxorubicin, and cyclophosphamide; 5FU + LV, 5-fluorouracil + leucovorin.
75 STANDARDIZED CANONICAL DISCRIMINANT FUNCTION COEFFICIENTS FUNC 1 FAC1 0.