FABP3


Also found in: Acronyms.

FABP3

A gene on chromosome 1p33-p32 that encodes a fatty acid-binding protein thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP3 plays a role in arresting growth of mammary epithelial cells and is a candidate tumour suppressor gene for breast cancer.
References in periodicals archive ?
Lipid metabolism: The following genes were categorized into the lipid metabolism pathway: PLTP (lipid transport); SCD (lipogenesis); liver X receptor a, nuclear receptor subfamily 1, group H, member (LR1H3) (cholesterol metabolism); FABP3 (fatty acid transport); CPT2, ACADL, and ACOX2 (fatty acid oxidation); and FABP4 (adipocyte differentiation).
Palmitate and stearate suppressed linearly or quadratically the expression of ACACA, FASN, and FABP3, but had the opposite effect on CD36 and CSN1S1 mRNA abundance.
ACSL1, AGPAT6, FABP3, LPIN1, and SLC27A6 are the most abundant isoforms in bovine mammary tissue and their expression is affected by stage of lactation.
In the present study, TZD could activate PGC1, and up-regulate its expression in muscle cells or adipocytes in muscle adipose tissue of the TZD-treated pigs, subsequently the expression of the downstream genes such as FABP3, which involved in PPAR[gamma] pathway, will be increased to enlarge the effect of TZD supplementation.
Dietary TZD supplementation could increase the ADG and decrease the F:G ratio, and elevate the serum TG and HDL levels, importantly, had a positive effect on marbling score and IMF content, which was related with PGC-1 and FABP3, the genes involved in fat metabolism.
369 intestinal fatty acid binding protein 3, FABP3 0.