LZTS1

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LZTS1

A gene on chromosome 8p22 that encodes a tumour-suppressor protein ubiquitously expressed in normal tissue. LZTS1 has a role in cell cycle control by interacting with the Cdk1/cyclinB1 complex and preventing uncontrolled cell proliferation.

Molecular pathology
Loss of heterozygosity in chromosome 8p is linked to various cancers; LZTS1 is normally expressed in low-grade or non-metastasising uveal melanomas, and silenced in aggressive and metastasising forms.
References in periodicals archive ?
Jenkins isn't Wales' only beneficiary of the SEE Next Generation programme with T37/ F37 sprinter Jenny McLoughlin also making the cut along with Cardiff JIF Cycling Club's Emily Tillett.
In the F37 discus throw competition, Oman's Zainab Mohammed won the bronze.
The Shotton athlete had finished sixth in the F37 shot putt earlier in the week.
Earlier in the day, Beverley Jones helped the cause by winning bronze in the women's F37 discus with a throw of 28.
Meanwhile, North Wales' own Bev Jones competes in the F37 discus today following her seventh place in the shot putt on Tuesday.
This Notice applies to the following programs: D43, D71, F05, F30, F31, F32, F33, F34, F37, F38, K01, K02, K05, K07, K08, KU12, K18, K22, K23, K24, K25, K26, K30, K99/R00, KL1 KL2, R25, R36, T15, T32, T34, T35, T36, T37, T90/R90, TL1, TU2, and U2R.
Meshaima, an employee at the National Institute for the Disabled, falls into the F31 to 38 class and will be competing in the F37 shot put and discus throw events.
5--Source: Registration of programs and the critical Factors detected in this research NUMBER OF PROGRAMS FOR EACH CRITICAL FACTOR Critical No of Critical No of Factors Programs Factors Programs F1 5 F20 1 F2 4 F21 0 F3 2 F22 1 F4 0 F23 2 F5 2 F24 0 F6 2 F25 0 F7 1 F26 0 F8 2 F27 1 F9 2 F28 0 F10 0 F29 1 F11 1 F30 2 F12 3 F31 0 F13 0 F32 1 F14 0 F33 1 F15 0 F34 0 F16 1 F35 0 F17 1 F36 0 F18 0 F37 2 F19 0 F38 0
Stand F37 Contact SpiroflowLtd on 01200 422525 or visit www.
Durham City Harrier Ken Churchill smashed his own world javelin record with his first throw in the F37 final at the Paralymic Games in Athens.