FBXW10

(redirected from F-box and WD-40 domain protein 10)

FBXW10

A gene on chromosome 17p12 that encodes a so-called F-box protein, which contains a 40 amino acid protein-interacting motif (the F box). F-box proteins form a complex with SKP1 and cullin, resulting in phosphorylation-dependent ubiquitination and ubiquitin mediated degradation of targeted proteins.
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