SHROOM3

(redirected from F-actin-binding protein)

SHROOM3

A gene on chromosome 4q21.1 that encodes a PDZ-domain-containing protein that belongs to a family of Shroom-related proteins, which may be involved in regulating cell shape. A homologue in mice is required for proper neurulation.
References in periodicals archive ?
A hydrophobic pocket in subdomain 1, located at the entrance of the hydrophobic cleft, appears to be a primary target for both G-actin- and F-actin-binding proteins, including Gc-globulin (18).