F-actin


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Related to F-actin: phalloidin, G-actin, Vinculin

F-ac·tin

(ak'tin),
the association of G-actin subunits into a fibrous (F) protein caused by an increase in salt concentration; the conversion of G-actin to F-actin is catalyzed by small concentrations of magnesium ion, is reversible, and is accompanied by the conversion of the bound ATP molecule to ADP and phosphate and the conversion of one reactive -thiol group to an unreactive form.

F-ac·tin

(ak'tin)
The association of G-actin subunits into a fibrous (F) protein.
References in periodicals archive ?
Specifically, shrunken cells and F-actin accumulation were observed after nicotine treatment.
d) Fluorescence microscopy observed the increased H9c2 cells surface area of F-actin staining in PA group, which was suppressed by Nec- 1 (10 nM), according to the semiquantitative results by ImageJ software, n = 3.
Abbreviations: F-actin, filamentous actin; FITC, fluorescein isothiocyanate; FSW, filter-sterilized seawater; LPS, lipopolysaccharide; MMP, matrix metalloproteinase(s); mPBS, marine phosphate buffered saline; TCT, tracheal cytotoxin.
Unipolar reorganization of F-actin layer at bacterial division and bundling of actin filaments by plastin correlate with movement of Shigella flexneri within HeLa cells.
As cell migration is related to reorganization of the actin cytoskeleton, we also measured the cytoskeletal actin organization by staining F-actin with phalloidin in PC-3 cells and DU145 cells.
25% bovine serum albumin for 30 min, and stained with phalloidin and DAPI solution to visualize F-actin and nuclei, respectively (Life Technology, Seoul, Korea).
Focal adhesion kinase is a regulator of F-actin dynamics: New insights from studies in the testis," Spermatogenesis 3(3): e25385.
Prior to neural tube closure, F-actin is accumulated at the medial plane of the epidermal cells adjacent to the neural plate.
Next, the study looked at F-actin filaments, a protein structure which previous studies have shown plays a role in the constriction of ASM, and found that 6-shogaol was effective in speedily dissolving these filaments.
vc]) covalently binds to G-actin and F-actin, and causes actin depolymerization, which leads to cell rounding (Kudryashov et al.
Finally, to test whether the anti-actin ELISA used was specific for F-actin, we assayed for IgG anti-F-actin in 18 sera from patients with type 1 AH, positive by IF for IgG anti-F-actin on HEP-2 cells (titer range, 1:160 -1:1280), and 30 negative sera from healthy controls.