extramammary Paget's disease


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extramammary Paget's disease

[-mam′ərē]
Etymology: L, extra, outside, mamma, breast; James Paget, English surgeon, 1814-1899; L, dis + Fr, aise, ease
a gradually spreading red, scaly, and crusted lesion resembling that of Paget's disease but not occurring on the breast. A common area is the vulva. The lesions give rise to carcinoma in approximately 50% of the cases.

extramammary Paget's disease

 A lesion similar to Paget's disease of breast, less often linked to underlying malignancy; the condition arises from skin adnexae, visceral malignancy or rarely, de novo, in scrotum, perineum, labia majora; cells are more often mucin-positive than in Paget's disease of breast
References in periodicals archive ?
Vulvar clear cells of Toker: precursors of extramammary Paget's disease.
The role of immunohistochemistry in discriminating primary from secondary extramammary Paget's disease.
Alternatively, malignancies such as extramammary Paget's disease may masquerade as lichen sclerosus (3).
Extramammary Paget's disease masquerading as lichen sclerosus.
Extramammary Paget's disease is most often found in the vulvar area and usually has an excellent prognosis, Peter J.
The vulva is the site of about 65% of extramammary Paget's disease (EMPD), which accounts for about 1% of all vulvar malignancies, said Dr.
Cytokeratin 7 staining in mammary and extramammary Paget's disease.
Treatment of primary limited cutaneous extramammary Paget's disease with topical imiquimod monotherapy: two case reports.
Successful treatment of extramammary Paget's disease of the scrotum with imiquimod 5% cream.
Gross cystic disease fluid protein-15 reactivity in extramammary Paget's disease with and without associated internal malignancy.
Cytokeratins, CEA, and mucin histochemistry in the diagnosis and characterization of extramammary Paget's disease.