exosome

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exosome

(ĕk′sō-sōm′)
n.
1. A tiny vesicle created and released from the plasma membrane of various types of cells, especially immune cells, and capable of inducing antigen-specific immune responses.
2. A cellular protein complex containing enzymes that degrade nuclear and cytoplasmic RNA.

exosome

(ĕks′ō-sōm″) [″ + Gr. soma, body]
An intracellular complex that degrades and processes messenger RNA molecules.

exosome

a protein complex containing NUCLEASES involved in degrading mRNA in eukaryotes.
References in periodicals archive ?
The lead therapeutic candidate is the Aethlon Hemopurifier, a first-in-class device that targets the rapid elimination of infectious viruses and cancer promoting exosomes from the circulatory system of treated individuals.
Kishore's team published the first paper ever looking at stem cell exosomes and heart repair -- making the team a pioneer in the field of exosomes and a trailblazer in the use of exosomes in heart disease.
The company's lead product is the Aethlon Hemopurifier, a first-in- class device that selectively targets the rapid elimination of circulating viruses and tumor-secreted exosomes that promote cancer progression.
Moreover, the exosomes are immuno-privileged and can pass through the blood-brain barrier.
These cancer exosomes essentially act as mini tumour "satellites" that hijack and neutralise invading anti-tumour cells that are recruited to the prostate tumour to eradicate the cancer.
The exosomes are injected into the blood and are able to carry the drugs past the blood-brain barrier.
15) showed that exosomes contain mRNA and microRNA that can be transferred between cells, and Luo et al.
Exosomes are released from various cell types, and are found under both normal and pathological conditions, including cancer.
Exosomes are found in urine from people with and without cancer, but seem to be excreted in large quantities by some cancer cells.
The fact that we can harvest this important cancer signature from exosomes circulating in blood is a critical demonstration of Exosome's technology for advanced personalized medicine diagnostics", said James R.
A few investigators even suggest that HIV, the AIDS virus, exploits exosomes to spread copies of itself among cells (SN: 12/6/03, p.