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excitotoxicity

   Also found in: Wikipedia 0.03 sec.
excitotoxicity
exaggerated and continuous stimulation by a neurotransmitter, especially in those neuronal systems which use glutamate as the transmitter.
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Lau hypothesizes that ingestion of the well-established neurotoxicants aspartic acid and L-glutamic acid as additives could lead to a high enough body burden to kill neurons by a mechanism called excitotoxicity.
Adding up to no good? by Szpir, Michael / Environmental Health Perspectives
Dubner and Ruda (53) suggested that, in the event of prolonged hyperexcitability and hyperalgesia, a pathological state may develop involving excitotoxicity, cellular dysfunction, and loss of descending control mechanisms.
A comparison of pressure pain detection thresholds in people with ... by Battie, Michele C. / Physical Therapy
Viral-induced spinal motor neuron death is non-cellautonomous and involves glutamate excitotoxicity.
Virology, pathology, and clinical manifestations of West Nile Virus ... by Campbell, Grant L. / Emerging Infectious Diseases
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