Excision repair mechanism | definition of Excision repair mechanism by Medical dictionary
excision repair (redirected from Excision repair mechanism)
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the use of a complementary DNA strand as a template to replace a damaged segment of DNA.
excision repair Correction of DNA damage by the removal of the damaged length of single strand by one of a number of enzymes capable of recognizing damaged nucleotides, and resynthesizing the correct nucleotide sequence complementary to the normal strand. The repair is catalyzed by DNA polymerase I and DNA ligase.
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In contrast to other cytotoxic agents, Yondelisao preferentially targets cells with an intact nucleotide excision repair mechanism