excision repair

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ex·ci·sion re·pair

the use of a complementary DNA strand as a template to replace a damaged segment of DNA.

excision repair

Correction of DNA damage by the removal of the damaged length of single strand by one of a number of enzymes capable of recognizing damaged nucleotides, and resynthesizing the correct nucleotide sequence complementary to the normal strand. The repair is catalyzed by DNA polymerase I and DNA ligase.

excision repair

the removal of damaged polynucleotide segments from DNA (e.g. THYMINE DIMERS produced by ultraviolet light) and replacement with a correct segment using DNA POLYMERASE and DNA LIGASE.
References in periodicals archive ?
In contrast to other cytotoxic agents, Yondelisao preferentially targets cells with an intact nucleotide excision repair mechanism.