euthyroid sick syndrome (redirected from Euthyroid sick syndromes)

euthyroid

having a normally functioning thyroid gland.

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euthyroid sick syndrome

a euthyroid state in which extrathyroidal factors cause a reduction of serum T₃ or T₄ and elevation of reverse T₃ levels. Seen in patients with systemic illness, trauma, fever, starvation, treatment with glucocorticoids, etc. May be a protective metabolic effect.

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euthyroid sick syndrome

Lab medicine A “condition” in Pts who are critically ill with nonthyroid diseases that alter serum levels of thyroid hormones which, in absence of underlying nonthyroid illness, would be correctly interpreted as indicating a disease of the thyroid 'axis' Lab Peripheral ↓/inhibition of 5'-deiodinase, the deiodination enzyme, resulting in ↓ peripheral 5'-monodeiodination of thyroxine–T₄, reversed, free, and total T₃; TSH, TRH, and usually free thyroxine levels are normal. See Hyperthyroidism, Hypothyroidism.