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euthyroid sick syndrome |
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euthyroid having a normally functioning thyroid gland. euthyroid sick syndrome a euthyroid state in which extrathyroidal factors cause a reduction of serum T3 or T4 and elevation of reverse T3 levels. Seen in patients with systemic illness, trauma, fever, starvation, treatment with glucocorticoids, etc. May be a protective metabolic effect. euthyroid sick syndrome Lab medicine A “condition” in Pts who are critically ill with nonthyroid diseases that alter serum levels of thyroid hormones which, in absence of underlying nonthyroid illness, would be correctly
interpreted as indicating a disease of the thyroid 'axis' Lab Peripheral ↓/inhibition of 5'-deiodinase, the deiodination enzyme, resulting in ↓ peripheral 5'-monodeiodination of thyroxine–T4,
reversed, free, and total T3; TSH, TRH, and usually free thyroxine levels are normal. See Hyperthyroidism, Hypothyroidism. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| ? Mentioned in | ? References in periodicals archive | |
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Based upon the conviction that patients with systemic illnesses are euthyroid, Wartofsky and Bunnan (14) in 1982 used the term euthyroid sick syndrome to describe the spectrum of thyroid abnormalities a ssociated With nonthyroidal illness. Vexiau P, Perez-Castiglioni P, Socie G, et al: 'The euthyroid sick syndrome. |
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