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euthyroid sick syndrome

   Also found in: Wikipedia 0.01 sec.
euthyroid
having a normally functioning thyroid gland.

euthyroid sick syndrome
a euthyroid state in which extrathyroidal factors cause a reduction of serum T3 or T4 and elevation of reverse T3 levels. Seen in patients with systemic illness, trauma, fever, starvation, treatment with glucocorticoids, etc. May be a protective metabolic effect.

euthyroid sick syndrome
Lab medicine A “condition” in Pts who are critically ill with nonthyroid diseases that alter serum levels of thyroid hormones which, in absence of underlying nonthyroid illness, would be correctly interpreted as indicating a disease of the thyroid 'axis' Lab Peripheral ↓/inhibition of 5'-deiodinase, the deiodination enzyme, resulting in ↓ peripheral 5'-monodeiodination of thyroxine–T4, reversed, free, and total T3; TSH, TRH, and usually free thyroxine levels are normal. See Hyperthyroidism, Hypothyroidism.


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1) Euthyroid sick syndrome A distinguishing characteristic of euthyroid sick syndrome, which is seen in clinically euthyroid patients suffering from nonthyroidal systemic illness is the presence of abnormal thyroid function tests.
Euthyroid sick syndrome The hypothalamic-pituitary-thyroid axis is affected by a nonthyroid illness.
3] in treating primary hypothyroidism and the euthyroid sick syndrome, none of these applications is supported by reasonable clinical data--and in the case of euthyroid sick syndrome, there is a distinct potential for harm, according to the panelists.
 
 
 
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