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etomidate

   Also found in: Wikipedia 0.06 sec.
etomidate /etom·i·date/ (ĕ-tom´ĭ-dāt) a sedative-hypnotic, administered intravenously for the induction and maintenance of anesthesia.
etomidate
[etom′idāt]
a short-acting, hypnotic nonbarbiturate IV agent for induction of general anesthesia. It has minimal adverse cardiovascular and respiratory effects, thus providing a greater margin of safety in patients with or at risk for heart disease. Adverse effects include transient reduction in adrenal gland cortisol release, pain on injection, and involuntary muscle movements.

etomidate
an intravenous, nonbarbiturate, fast-inducing anesthetic with no analgesic effect. Also causes suppression of adrenal steroidogenesis and may be used in the treatment of hyperadrenocorticism.


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An injection of etomidate or propofol prevented this reflex in typical mice but not in the knockin mice with the mutant GABA-A receptor, the team reported in the Feb 17, 2003 FASEB Journal.
Effects of metyrapone and etomidate on adrenal function and growth rate in female rats.
 
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