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Estrogen
(redirected from Estrogenicity)

   Also found in: Encyclopedia, Wikipedia 0.01 sec.
estrogen /es·tro·gen/ (es´tro-jen) a generic term for estrus-producing compounds; the female sex hormones, including estradiol, estriol, and estrone. In humans, the estrogens are formed in the ovary, adrenal cortex, testis, and fetoplacental unit, and are responsible for female secondary sex characteristic development, and, during the menstrual cycle, act on the female genitalia to produce an environment suitable for fertilization, implantation, and nutrition of the early embryo. Uses for estrogens include oral contraceptives, hormone replacement therapy, advanced prostate or postmenopausal breast carcinoma treatment, and osteoporosis prophylaxis.
conjugated estrogens  a mixture of the sodium salts of the sulfate esters of estrone and equilin, having the actions and uses of estrogens.
esterified estrogens  a mixture of the sodium salts of esters of estrogenic substances, principally estrone; the uses are those of estrogens.

es·tro·gen or oes·tro·gen (str-jn)
n.
Any of several natural or synthetic substances formed by the ovary, placenta, testis, and certain plants, that stimulate the female secondary sex characteristics, exert systemic effects such as the growth and maturation of long bones, and are used to treat disorders due to estrogen deficiency and to ameliorate cancers of the breast and prostate. Also called estrin.

Estrogen
Female hormone produced by the ovaries and released by the follicles as they mature. Responsible for female sexual characteristics, estrogen stimulates and triggers a response from at least 300 tissues, and may help some types of breast cancer to grow. After menopause, the production of the hormone gradually stops.

estrogen (esˑ·tr·jin),
n hormone that maintains secondary female sex characteristics.

estrogen
a generic term for estrus-producing compounds; the naturally occurring female sex hormones include estradiol, estriol and estrone.
In animals the estrogens are formed in the ovary, adrenal cortex, testis and fetoplacental unit, and are responsible for female secondary sex characteristic development, and act on the female genitalia to produce an environment suitable for fertilization, implantation and nutrition of the early embryo. A very important function is the creation of a state of sexual receptivity in the female.

conjugated e's
a mixture of sulfate esters of estrogenic substances, principally estrone and equilin; the uses are those of estrogens.
esterified e's
a mixture of esters of estrogenic substances, principally estrone; the uses are those of estrogens.
fungal estrogen
Fusarium graminearum (F. roseum) produces zearalenone which has estrogenic activity.
placental estrogen
see estrogen (above).
plant estrogen
subterranean and red clover may contain significant amounts of an isoflavone, genistein, with estrogenic activity. See also estrogenism.
estrogen poisoning
estrogen-responsive dermatosis
a bilaterally symmetrical alopecia, sometimes with seborrhea, seen in spayed bitches; responsive to treatment with estrogens such as diethylstilbestrol.

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Food (Rodent Diet 2018; Harlan Teklad, Madison, WI), cages, and bedding tested negligible for estrogenicity by the E-SCREEN assay (Soto et al.
Although some of these compounds may have only weak endocrine-disrupting activities, the combined burden of estrogenicity and genomic instability could produce more detrimental effects than estrogenic action alone.
In terms of estrogenicity, glycitein appears to top both daidzein and genistein, the Iowa scientists report in the April JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.
 
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