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estramustine

   Also found in: Wikipedia 0.09 sec.
estramustine /es·tra·mus·tine/ (-mus´tēn) an antineoplastic containing estradiol joined to mechlorethamine, used for palliative treatment of metastatic or progressive carcinoma of the prostate; used as e. phosphate sodium.
estramustine
[es′trämus′tēn]
an antineoplastic agent containing estradiol joined to mechlorethamine, administered orally for palliative treatment of metastatic or progressive carcinoma of the prostate. It is used as estramustine phosphate sodium.

estramustine
Oncology A combination of estradiol and nitrogen mustard used in the palliative therapy of prostate CA. See Prostate CA.


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The chemotherapies administered to patients in Groups B and C were very similar and consisted of mitoxantrone plus prednisone or estramustine phosphate.
Clinical trials have shown the lack of activity of estramustine in hormone refractory prostate cancer, but the drug is still commonly used because of the lack of alternatives.
Clinical trials have shown the lack of activity of estramustine in hormone refractory prostate cancer, but the drug is still commonly used because of the lack of alternatives.
 
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