erythroleukemia /eryth·ro·leu·ke·mia/ (ĕ-rith″ro-loo-ke´me-ah) a malignant blood dyscrasia, one of the myeloproliferative disorders, with atypical erythroblasts and myeloblasts in the peripheral blood.
erythroleukemia
erythroleukemia
e·ryth·ro·leu·ke·mi·a ( -rth r -l -k  m- )n. A malignant disorder characterized by the proliferation of erythroblastic and leukoblastic tissues. |
erythroleukemia
[-lo̅o̅kē′mē·ə]
Etymology: Gk, erythros + leukos, white, haima, blood
a malignant blood disorder characterized by a proliferation of erythropoietic elements in bone marrow, erythroblasts with bizarre lobulated nuclei, and abnormal myeloblasts in peripheral blood. The disease may have an acute or chronic course. Also called Di Guglielmo's disease, Di Guglielmo's syndrome, erythromyeloblastic leukemia.
erythroleukemia
a malignant blood dyscrasia of dogs and cats; one of the myeloproliferative disorders, with atypical erythroblasts and myeloblasts in the peripheral blood.
erythroleukemia
Di Guglielmo syndrome Hematology An acute myelocytic leukemia–FAB classification, M6, which is usually acquired affecting the elderly, but rarely also AD Clinical Anemia, fever, hepatosplenomegaly, hemorrhagic diathesis
Lab ↑ Erythroblasts in circulation, BM, ↑ gammaglobulins, false positive positive rheumatoid factor, ANA, Coombs antiglobulin Genetics Aneuploidy–63%; cytogenetic defects, especially chromosomes 5 and 7 Prognosis Poor. Cf
French-American-British classification.
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