erythroleukemia

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Related to Erythroleukemias: hemianalgesia, erythrotoxin

erythroleukemia

 [ĕ-rith″ro-loo-ke´me-ah]
a malignant blood dyscrasia, one of the myeloproliferative disorders, with atypical erythroblasts and myeloblasts in the peripheral blood.
acute erythroleukemia a form of acute myelogenous leukemia representing erythroleukemia in which malignant leukocyte precursors have proliferated and become predominant.

e·ryth·ro·leu·ke·mi·a

(ĕ-rith'rō-lū-kē'mē-ă),
Simultaneous neoplastic proliferation of erythroblastic and leukoblastic tissues.

erythroleukemia

/eryth·ro·leu·ke·mia/ (ĕ-rith″ro-loo-ke´me-ah) a malignant blood dyscrasia, one of the myeloproliferative disorders, with atypical erythroblasts and myeloblasts in the peripheral blood.

erythroleukemia

[-lo̅o̅kē′mē·ə]
Etymology: Gk, erythros + leukos, white, haima, blood
a malignant blood disorder characterized by a proliferation of erythropoietic elements in bone marrow, erythroblasts with bizarre lobulated nuclei, and abnormal myeloblasts in peripheral blood. The disease may have an acute or chronic course. Also called Di Guglielmo's disease, Di Guglielmo's syndrome, erythromyeloblastic leukemia.
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Erythroleukemia

erythroleukemia

Di Guglielmo syndrome Hematology An acute myelocytic leukemia–FAB classification, M6, which is usually acquired affecting the elderly, but rarely also AD Clinical Anemia, fever, hepatosplenomegaly, hemorrhagic diathesis Lab ↑ Erythroblasts in circulation, BM, ↑ gammaglobulins, false positive positive rheumatoid factor, ANA, Coombs antiglobulin Genetics Aneuploidy–63%; cytogenetic defects, especially chromosomes 5 and 7 Prognosis Poor. See French-American-British classification.

e·ryth·ro·leu·ke·mi·a

(ĕ-rith'rō-lū-kē'mē-ă)
Simultaneous neoplastic proliferation of erythroblastic and leukoblastic tissues.
Synonym(s): erythroleukaemia.

erythroleukemia

a malignant blood dyscrasia of dogs and cats; one of the myeloproliferative disorders, with atypical erythroblasts and myeloblasts in the peripheral blood.
References in periodicals archive ?
Because of the rarity of AEL, relatively few cases have been assessed at the molecular level, and the cases assessed have been primarily of the erythroleukemia subtype.
There is a subset of cases of AEL, erythroleukemia subtype, in which the overall blast count can be low.
For the erythroleukemia subtype, the most important entities in the differential diagnosis include MDS with erythroid predominance, AML with myelodysplasia-related changes, and other types of AML with increased erythroid precursors.
35) Morphologically, erythroid dysplasia and ring sideroblasts are commonly observed in MDS as well as in the erythroleukemia subtype of AEL.
Cases of AML with myelodysplasia-related changes can be erythroid rich, with 50% or more erythroid precursors, but these cases are not classified as AEL, erythroleukemia subtype with current WHO criteria.
As is illustrated in this discussion of the differential diagnosis, the diagnosis of erythroleukemia is, in part, one of exclusion.
In one study, (40) AEL of the erythroleukemia subtype had very high levels of P-glycoprotein expression as compared to that of other types of AML.
Diagnosis and characterization of acute erythroleukemia subsets by determining the percentages of myeloblasts and proerythroblasts in 69 cases.
Severe hemolysis as presenting sign of acute erythroleukemia.
Acute erythroleukemia with der(1;7)(q10;p10) as a sole acquired abnormality after treatment with azathioprine.
Complete remission induced by high dose erythropoietin and granulocyte colony stimulating factor in acute erythroleukemia (AML-M6 with maturation).