hematopoietic stem cell

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hematopoietic stem cell

an actively dividing cell that is capable of self-renewal and of differentiation into any blood cell lineage.

hematopoietic stem cell

A progenitor cell in the bone marrow that can replicate itself as well as produce precursor cells of the various blood cell lineages.
See also: cell

Hematopoietic stem cell

A cell that can develop into any type of specialized blood cell.
References in periodicals archive ?
Primary polycythemia relates to defects in erythroid progenitor cells (EPCs), with polycythemia vera being the most common form (7), (8).
PRCA exists in several forms, and the most common is an acute self-limited condition (10) that is secondary to virus- and drug-induced impairment of erythroid progenitor cells (9), (11).
EPO stimulates erythropoiesis by binding to its receptor (EPO-R) on the surface of erythroid progenitor cells, promoting their proliferation and differentiation and maintaining their viability.
ACD is immune driven where inflammatory cytokines and cells of the reticuloendothelial system (RES) induce changes in iron homeostasis, the proliferation of erythroid progenitor cells, the production of erythropoietin (EPO), and the life span of the red cell.
It infects actively replicating cells, specifically erythroid progenitor cells, and causes lysis of these red cell precursors, resulting in decreased red cell production.
Inflammation-induced synthesis of hepcidin plays a crucial role in macrophage iron retention, which underlies the anemia of chronic disease by limiting the availability of iron for erythroid progenitor cells.
S110 increases fetal hemoglobin and reduces DNA methylation in non-human primates and in cultured human erythroid progenitor cells
Cytokine-induced synthesis of hepcidin plays a crucial role in macrophage iron retention, which underlies the anemia of chronic disease by limiting the availability of iron for erythroid progenitor cells.
Cytokine-induced synthesis of hepcidin plays a crucial role in macrophage iron retention, which underlies the anemia of inflammation by limiting the availability of iron for erythroid progenitor cells.
Ligand tested the effect of LG5640 on EPO-dependent cell lines and in cultures of CD34-positive human bone marrow cells, a well-established model for the effects of EPO on erythroid progenitor cells and their maturation into red blood cells (erythropoiesis).
FibroGen's Phase I SBIR research showed that HIF-PH inhibitors with demonstrable erythropoietic effects can also act alone or in synergy with hydroxyurea to raise levels of HbF in human erythroid progenitor cells.
2002) Conserved, erythropoietin-responsive VL30 promoters isolated from erythroid progenitor cells.