levamisole

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levamisole

 [le-vam´ĭ-sōl]
an oral imidazole that enhances the immume response and is used as the hydrochloride salt as an adjuvant to fluorouracil in antineoplastic therapy after surgery in patients with Dukes' stage C colon cancer.

le·vam·i·so·le

(lē-vam'ĭ-sōl),
Formerly used as an anthelmintic; increases immune responses and is used adjunctively with fluorouracil to improve response and suppress recurrence.

levamisole

/le·vam·i·sole/ (le-vam´ĭ-sōl) an immunomodulator used with fluorouracil in the treatment of colon cancer, administered as the hydrochloride salt.

levamisole

an immunomodulator used as an adjuvant treatment in combination with fluorouracil after surgical resection in patients with Dukes' stage C colon cancer.

levamisole

Oncology A broad-spectrum anthelmintic that stimulates immune function, enhancing hypersensitivity; it has been used with 5-FU to ↑ Pt survival in advanced colorectal and other CAs Adverse effects N&V, diarrhea, rash, flu-like Sx. See Unproven methods for cancer management Parasitology An l- form of tetramisole, which is most commonly used anthelmintic for roundworm, hookworm, Strongyloidesinfections.

le·vam·i·sole

(lē-vam'ĭ-sōl)
Drug that increases immune responses; used adjunctively with fluorouracil to improve response and suppress recurrence.

levamisole

An ANTHELMINTIC drug used to remove roundworms. It has also been found to have an unexpected effect in stimulating the immune system by increasing T cell responsiveness and encouraging the activity of polymorphonuclear LEUCOCYTES and MACROPHAGES. It is effective in rheumatoid arthritis. Adverse side effects limit its use. The drug is on the WHO official list.

levamisole

a broad-spectrum anthelmintic of proven efficiency against gastrointestinal and lung worms that can be administered orally, by injection and by pour-on in cattle. It has no effect on tapeworms or liver fluke; it has a secondary effect in enhancing depressed immune responsiveness by stimulation of T lymphocytes and phagocytosis.

levamisole poisoning
causes a syndrome of lip licking, head shaking, salivation, tremor, excitement and increased frequency of urination and defecation.