MIER1

(redirected from Er13)

MIER1

A gene on chromosome 1p31.3 that encodes a transcription repressor which regulates the expression of various genes, possibly by recruiting HDAC1, a histone deacetylase involved in chromatin silencing.
References in periodicals archive ?
This is important because ER13 mediates a bone sparing effect via an increase in the ratio of OPG to RANKL, in a manner differentially affected by steroids other than [E.
To evaluate ERE-mediated transcriptional activity of ERa and ER13, we examined promoter activation in Ishikawa, HeLa, and HepG2 cells.
Expression of HIF-1[alpha]-dependent P-gp was not completely diminished in the presence of curcumin because P-gp can be regulated by other signaling pathways, such as NF-kB, YB-1, AP-1, ER13 and PXR as well (Higgins 2007).