epigallocatechin gallate

(redirected from Epigallocatechin-3-gallate)
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epigallocatechin gallate

Alternative pharmacology
A substance present in green tea that is an antioxidant, reduces blood pressure and lowers the total and low-density lipoprotein-cholesterol, while raising the high-density lipoprotein cholesterol.

epigallocatechin gallate

(ĕp″ĭ-găl′ō-kăt-ĕ-chĭn găl′lāt),

EGCg, EGCG

A polyphenol compound present in green tea that inhibits the growth of cancer cells in the laboratory. Its effect on patients with cancer is unknown.
References in periodicals archive ?
The method is comprised of providing a composition consisting of caffeine, saw palmetto berry derivative, epigallocatechin-3-gallate (EGCG) derivative, D1 water, sodium C14-16 olefin sulfonate; cocamidopropyl betaine; cocamide DEA; dimethiconol dodecylbenzensulfonate; TEA dodecylbenzensulfonate; glycol distearate; sodium chloride; fragrance; hydrolyzed wheat protein; guar hydroxypropyltrimonium chloride; panthenol; methylchloroisothiazolinone; methylisothiazolinone and citric acid.
Epigallocatechin-3-gallate (EGCG) is the most abundant and potent catechin found in green tea responsible for these cancer prevention effects.
The purpose of this study was to examine whether epigallocatechin-3-gallate (EGCG) prevents TNF-[alpha]-dependent endothelial dysfunction.
Activity of Green Tea Polyphenol Epigallocatechin-3-gallate Against Ovarian Carcinoma Cell Lines.
Now we are finding that a molecule in green tea, Epigallocatechin-3-gallate, or EGCG, interferes with the formation of these unwanted and dangerous amyloid plaques.
The specific molecule in green tea, epigallocatechin-3-gallate, also known as EGCG, prevented aggregate formation and broke down existing aggregate structures in the proteins that contained metals-specifically copper, iron and zinc.
Researchers who fed a chemical - called Epigallocatechin-3-gallate, or EGCG - in the tea to mice on a fatty diet found they got heavier 45% more slowly.
Epigallocatechin-3-gallate functions as an inhibitor of certain nuclear proteins important to the control (rate) of mitochondriogenesis and apoptosis.
Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells.
Green tea contains a potent mix of phytochemicals, of which the catechins, epigallocatechin-3-gallate (EGCG) and epigallocatechin, have been well studied.
The researchers said they determined that the green tea polyphenol, or vegetable tannin, called epigallocatechin-3-gallate (EGCG) is capable of neutralizing a protein in sperm which serves as a vector for viral transmission during sex.
Green tea polyphenol epigallocatechin-3-gallate suppresses collagen production and proliferation in keloids via inhibition of the STAT-3 pathway