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eosinophilia-myalgia syndrome

   Also found in: Wikipedia 0.01 sec.
eosinophilia-myalgia syndrome, tryptophan-induced,
a potentially fatal disorder resulting from ingestion of tryptophan. It is characterized by a symptom complex of severe muscle pain, tenosynovitis, muscle edema, and skin rash lasting several weeks.


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The numerous social, clinical, and research problems dealt with during this epidemic have provided a basis for the study of other similar episodes, such as the eosinophilia-myalgia syndrome (EMS) epidemic (Kilbourne 1992), and other recent important problems in food processing and sales, such as new-variant Creutzfeld-Jacob disease (Tyler 2003) and the recent episode of contaminated chicken in Belgium (Van Larebeke et al.
FDA took action to limit the availability of L-tryptophan supplements because of the association between dietary supplements containing L-tryptophan and the 1989 epidemic outbreak of eosinophilia-myalgia syndrome (EMS) in the United States.
The new disease was called EMS, or Eosinophilia-Myalgia Syndrome, because patients have high levels of white blood cells called eosinophils and muscle pain (myalgia).
 
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