Eight of nine patients' ability to recognize the faces of specific people improved after receiving electrical pulses to the right side of the brain's entorhinal
area, which is critical to learning and memory.
In the majority of cases, tau pathology first appears in the memory centres of the brain, known as the entorhinal
cortex and hippocampal formation.
Low scores on the University of Pennsylvania Smell Identification Test (UPSIT) are linked to a thinning of the entorhinal
cortex the brain region where amyloid plaques are thought to first appear as Alzheimer's disease takes hold, reported at the Alzheimer's Association International Conference.
Inducible tau transgenic mouse models such as FVB-Tg (tetO-Tau[sub]P301L) 4510 have been established, where tau expression is confined to the entorhinal
cortex (EC) to mimic early tau pathology in AD.
The study builds on 2012 UCLA research published in the New England Journal of Medicine demonstrating that human memory can be strengthened by electrically stimulating the brain's entorhinal
Prenatal disturbances of nerve cell migration in the entorhinal
region: a common vulnerability factor in functional psychoses?
Scatterplots and correlations for cg24637308 (DNHD1 gene) methylation levels of blood DNA and four brain regions: prefrontal cortex (PC, n = 74), entorhinal
cortex (EC, n = 71), superior temporal gyrus (STG, n = 75), and cerebellum (CE, n = 71), based on an independent data set dominated by females (the female:male ratio was approximately 2:1) from (Hannon et al.
Tau immunostaining demonstrated characteristic pathology of argyrophilic grains in the amygdala, entorhinal
cortex, and hippocampus proper as well as scattered oligodendroglial "coiled" bodies in white matter.
A common thesis concerning the specific mechanisms involved in declarative episodic encoding is that MTL regions surrounding the hippocampus (namely the parahippocampal and entorhinal
cortex) receive sensorial information from different areas of the cortex.
G-CSF receptors are expressed in pyramidal neurons in the cortex (mainly layers II/III and V), the Purkinje cell layer of the cerebellum, the hippocampus (hilus and CA3 field), the entorhinal
cortex and the olfactory bulb.
Moser, "Topography of head direction cells in medial entorhinal
cortex," Current Biology, vol.
Results of the OPID-20 test showed significant differences among the four groups of participants, which correlated with the thinning of two brain regions: the hippocampus and the entorhinal
cortex (both of which are involved in memory), regions which have previously been linked to Alzheimer's risk.