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endothelin |
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endothelin (ET) [-thē′lin] any of a group of vasoconstrictive peptides produced by endothelial cells. Three known endothelins, designated ET-1, ET-2, and ET-3, are chemically related to asp venom. ET-1 is the most potent vasoconstrictor yet discovered, being 10 times stronger than the second-most potent vasoconstrictor known, angiotensin II. endothelin see endothelium-derived constricting factor. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Since the characterization of ET-1, 3 additional isoforms have been identified: endothelin-2 (ET-2), endothelin-3 (ET-3), and vasoactive intestinal constrictor polypeptide (VIC). |
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