LEFTY2

(redirected from Endometrial Bleeding-Associated Factor)
Also found in: Acronyms.

LEFTY2

A gene on chromosome 1q42.1 that encodes a member of the transforming growth factor beta (TGFB) family of cytokines that plays a role in determining left-right asymmetry during organogenesis and may also play a role in endometrial bleeding.
 
Molecular pathology
LEFTY2  mutations are associated with left-right axis malformations, especially in the heart and lungs; some types of infertility are associated with dysregulated LEFTY2 expression in the endometrium.