human endogenous retroviruses

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human endogenous retroviruses (HERV)

Retrovirus-like sequences found in the human genome, thought to constitute the remains of true retroviruses that were absorbed through evolution. At least one is thought to be linked to expression of tumor cells. They are also thought to be involved in autoimmune disorders such as multiple sclerosis.
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Host range and interference studies of three classes of pig endogenous retrovirus.
Over the past decade, an endogenous retrovirus named ERV-3 has drawn most of the attention of researchers trying to establish a role for viral proteins within the placenta.
Earlier this week, BioTransplant presented data indicating that the company may have developed a breed of pig that does not produce porcine endogenous retrovirus (PERV) which is capable of productively infecting human cells.
The most rigorous study undertaken to date on the safety of xenotransplantation has found no evidence of transmission of porcine endogenous retrovirus (PERV) infection in patients treated with pig tissue.
Conrad and his colleagues speculate that the production of superantigens by the activated endogenous retrovirus triggers the immune system to attack the pancreas.
BioTransplant Incorporated today (Nasdaq: BTRN) presented data indicating that the company may be able to develop a breed of pig that does not produce porcine endogenous retrovirus (PERV) capable of productively infecting human cells.
The companies say the study of Hormel Food and QPP pork slaughtering and processing workers will help determine whether porcine endogenous retrovirus (PERV), a virus found in all swine, is transferred to people who have a history of extensive exposure to swine tissues and fluids.
Most of those reports were suspect, she explains, because scientists could not distinguish at the time between MMTV-like viruses and human endogenous retrovirus (HER), an apparently ancient virus whose genetic code is integrated into everyone's genome.
19 /PRNewswire/ -- Evaluation of the largest ever retrospective study to assess the safety of xenotransplantation, the transplantation of cells, tissues or organs from one species to another, shows there is no evidence of Porcine Endogenous Retrovirus (PERV) infection in 160 patients previously treated with living pig tissue.