endocrine disruptor

(redirected from Endocrine disruption)

endocrine disruptor

A substance which interferes with the synthesis, secretion, transport, binding, action or elimination of natural hormones in the body that are responsible for development, behaviour, fertility and maintenance of homeostasis (normal cell metabolism).

Examples
DDT, polychlorinated biphenyls, bisphenol A, polybrominated diphenyl ethers, phthalates.

endocrine disruptor

(dĭs-rŭp′tĕr)
A chemical that may imitate or block the function of natural hormones if it is absorbed by the body. Many pesticides and plasticizing compounds, e.g., phthalates, are thought to disrupt endocrine pathways, esp. if they are absorbed by pregnant women during embryonic and fetal development.
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References in periodicals archive ?
Antibacterial soaps, contains chemical triclosan which is linked to endocrine disruption that mess up with your hormones and interfere with the reproductive system.
Exposure to them is linked to cancers, birth defects, impaired immunity, endocrine disruption and other ailments.
The launch of the validation study was announced on July 4 following an expert workshop on setting priorities for further development and validation of test methods for evaluating endocrine disruption held by DG Environment and the JRC in May/June.
Conclusions from various researchers or reviewers on endocrine disruption have sometimes been divergent or even contradictory, suggesting that our scientific understanding of the etiology of adverse outcomes in humans and wildlife through endocrine mechanisms is far from complete.
It will collect scientific information to develop a database on the toxicity of pesticides and capacity to cause endocrine disruption, especially in relation to water ecosystems and biodiversity.
Common chemicals of concern in tampons and pads can include dioxins and furans linked to cancer, endocrine disruption and reproductive toxicity; pesticide residues linked to cancer; and undisclosed fragrance ingredients, which may contain chemicals linked to cancer, endocrine disruption and allergens.
Envigo's current non-animal technology assays that comply with OECD regulatory guidelines span the fields of genetic toxicology, electrophysiology, metabolism, endocrine disruption, skin sensitization, skin and eye irritation, genomics and gene expression.
Our differing gender results suggest that androgenic endocrine disruption, to which male brains could be more sensitive, may explain the association.
Meanwhile, magazine and journal articles introduce students to timely topics such as BPA and endocrine disruption or the carcinogenic effects of pesticides, but don't provide the fundamentals needed to understand the science of toxicity.
Intersex in teleost fish: are we distinguishing endocrine disruption from natural phenomena?
Testing for endocrine disruption aims to identify the potential of a compound to disrupt the endocrine system.