fogo selvagem

(redirected from Endemic Pemphigus Foliaceus)

fo·go sel·va·gem

(fō'gō sel'vă-jem),
A form of pemphigus foliaceus, occurring in southern Brazil, in which the lesions are bullous, appear localized to the face and upper trunk, become widespread, variegated, erythrodermic, and exfoliative, and are immunologically indistinguishable from pemphigus foliaceus or vulgaris.
[Pg. wild fire]
A form of pemphigus foliaceus, an autoimmune blistering disorder, which is endemic in rural Colombia and Brazil
Epidemiology Fogo selvagem affects children and young adults and is distributed along rivers within the flying range of blackflies (Simuliidae), suggesting an environmental link
Management Steroids

fogo selvagem

(fo'go, goo sel-va'zhem) [Portuguese, literally “wild fire”],


An autoimmune disease that causes blistering of the skin of the head, neck or trunk, esp. when the skin is rubbed (Nikolsky's sign). It often causes a burning dysesthesia, from which its popular name is derived. The disease is typically found in Brazil or Colombia and has been associated with chronic or recurrent exposure to black flies. Synonym: endemic pemphigus foliaceus.


F., Brazilian physician.
Amendola syndrome - a form of pemphigus foliaceus that is endemic to Brazil. Synonym(s): Brazilian pemphigus; fogo selvagem; wildfire pemphigus
References in periodicals archive ?
The pathogenic effect of IgG4 autoantibodies in endemic pemphigus foliaceus (fogo selvagem).
Advances in pemphigus and its endemic pemphigus foliaceus (Fogo Selvagem) phenotype: a paradigm of human autoimmunity.
Endemic pemphigus foliaceus (EPF), or fogo selvagem, is a chronic autoimmune disease (1)fc characterized by the formation of intraepidermal blisters, which are attributed to the presence of immunoglobulin G4 (IgG4) and IgG1 autoantibodies against desmoglein 1 (2) that reduce the adhesion between keratinocytes.
High levels of interleukin-1 in patients with endemic pemphigus foliaceus.
Apoptosis and p63 expression in the pathogenesis of bullous lesions of endemic pemphigus foliaceus.