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Fogo Selvagem
(redirected from Endemic Pemphigus Foliaceus)

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Fogo Selvagem
A form of pemphigus foliaceus, an autoimmune blistering disorder, which is endemic in rural Colombia and Brazil
Epidemiology Fogo selvagem affects children and young adults and is distributed along rivers within the flying range of blackflies (Simuliidae), suggesting an environmental link
Management Steroids


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Endemic pemphigus foliaceus (EPF), or fogo selvagem, is a chronic autoimmune disease (1)fc characterized by the formation of intraepidermal blisters, which are attributed to the presence of immunoglobulin G4 (IgG4) and IgG1 autoantibodies against desmoglein 1 (2) that reduce the adhesion between keratinocytes.
 
 
 
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