End-stage lung disease

End-stage lung disease

The final stages of lung disease, when the lung can no longer keep the blood supplied with oxygen. End-stage lungs in pulmonary fibrosis have large air spaces separated by bands of inflammation and scarring.
Mentioned in: Pulmonary Fibrosis
References in periodicals archive ?
CF patients with Class I mutations typically experience more severe disease symptoms than those with other genotypes, including a shorter life span, a higher probability of end-stage lung disease, and a higher prevalence of pancreatic insufficiency.
Most remaining patients will experience a chronic course punctuated by exacerbations and remissions and will eventually develop end-stage lung disease with pulmonary fibrosis.
Cases that fall into this category often involve the gradual disintegration of the powers and capacities which make us human: severe instances of amyotropic lateral sclerosis, multiple sclerosis, Parkinson's disease, Lupus, end-stage lung disease, and perhaps advanced brain cancer or gastric cancer, There are patients in some of these conditions, although probably not very many, for whom hospice care does not work effectively.
The lung recipient had end-stage lung disease caused by pulmonary fibrosis.
For many patients with end-stage lung disease, lung transplant is the only option available, and it offers the chance for their quality of life to be significantly improved.
For patients with end-stage lung disease, lung transplantation can dramatically improve the patient's symptoms and offer relief from severe shortness of breath," said Dr.
CF patients with Class I mutations typically experience more severe disease symptoms than those with lower-risk genotypes, including a greater than twofold increased risk of death, a higher probability of end-stage lung disease and a higher prevalence of pancreatic insufficiency.
CF patients with Class I mutations typically experience more severe disease symptoms than those with low-risk genotypes, including a greater than twofold increased risk of death,(1) a higher probability of end-stage lung disease,(2) and a higher prevalence of pancreatic insufficiency.
A potential solution for patients with end-stage lung disease is donation after cardiac death (DCD).
But they concluded that, "unless survival without transplantation improves dramatically, transplantation should remain a therapeutic option for cystic fibrosis patients with end-stage lung disease.
Eight patients had end-stage lung disease and advanced liver disease; 1 had end-stage liver disease with compromised lung function.