Elimination half life | definition of Elimination half life by Medical dictionary
biological half-life (redirected from Elimination half life)
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Biology The time required for one half of the total amount of a particular substance in a biological system to be degraded by biological processes when the rate of removal is nearly exponential
the time required for the body to eliminate half of an administered dose of any substance by regular physiological processes. The biological half-life is approximately the same for stable and radioactive isotopes of a specific element. Also called metabolic half-life.
See also effective half-life, half-life
Nuclear physics The length of time required for one half of a radioactive substance to be biologically eliminated from the body
biological half-life T1/2 Biology The time required for 1⁄2 of the total amount of a particular substance in a biologic system to be degraded by biological processes when the rate of removal is nearly exponential Radiation physics The length of time required for1/2 of a radioactive substance to be biologically eliminated from the body
References in periodicals archive
The elimination rate constant (Kel) and elimination half life (t 1/2) were determined by log-linear regress on data from the terminal monoexponential phase of the concentration versus time profiles, while for calculating absorption rate constant (Ka) and absorption half life (t 1/2 a) method of residuals was used.
038 with corresponding elimination half life (t 1/2 b) of 5.
The results demonstrated in both healthy volunteers and cystic fibrosis patients similar pharmacokinetics of inhaled liposomal ciprofloxacin, with a long systemic elimination half life
(tu) of ~10.