biological half-life

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biological half-life

n.

biological half-life

the time required for the body to eliminate half of an administered dose of any substance by regular physiological processes. The biological half-life is approximately the same for stable and radioactive isotopes of a specific element. Also called metabolic half-life. See also effective half-life, half-life.
Biology The time required for one half of the total amount of a particular substance in a biological system to be degraded by biological processes when the rate of removal is nearly exponential
Nuclear physics The length of time required for one half of a radioactive substance to be biologically eliminated from the body

biological half-life

T1/2 Biology The time required for 1⁄2 of the total amount of a particular substance in a biologic system to be degraded by biological processes when the rate of removal is nearly exponential Radiation physics The length of time required for1/2 of a radioactive substance to be biologically eliminated from the body
References in periodicals archive ?
The elimination rate constant (Kel) and elimination half life (t 1/2) were determined by log-linear regress on data from the terminal monoexponential phase of the concentration versus time profiles, while for calculating absorption rate constant (Ka) and absorption half life (t 1/2 a) method of residuals was used.
038 with corresponding elimination half life (t 1/2 b) of 5.
The results demonstrated in both healthy volunteers and cystic fibrosis patients similar pharmacokinetics of inhaled liposomal ciprofloxacin, with a long systemic elimination half life (tu) of ~10.

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