Proteus Syndrome (redirected from Elephant man in context of NF)

Proteus syndrome

[prō′tē·us]

a rare congenital disorder with highly variable manifestations, including partial gigantism of the hands and feet with hypertrophy of the palms and soles, nevi, hemihypertrophy, subcutaneous tumors, macrocephaly and other skull abnormalities, and abdominal or pelvic lipomatosis. The cause is unknown, although a genetic origin, possibly of autosomal-dominant transmission, has been conjectured. Although symptoms can be treated, there is no known cure.

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Proteus Syndrome

A rare autosomal dominant [MIM 176920] condition characterised by acral gigantism, plantar hyperplasia, hemangiomas, lipomas, varicosities, linear verrucae, nevi, macrocephaly, cranial hyperostosis, pachydermy, and hypertrophy of long bones