electrospray ionization mass spectrometry


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electrospray ionization mass spectrometry

A method of mass spectrometry used to obtain the chemical analysis and weight of large molecules, especially proteins and peptides using a very small sample. The electrospray provides a charge on the molecules which are then injected into a mass spectrometer to determine the ratio of charge to molecular mass.
References in periodicals archive ?
Simultaneous identification of mycobacterial isolates to the species level and determination of tuberculosis drug resistance by PCR followed by electrospray ionization mass spectrometry.
Detection of heartworm infection in dogs via PCR amplification and electrospray ionization mass spectrometry of nucleic acid extracts from whole blood samples.
ramillorum, therefore extracts obtained from different plant parts were analyzed by electrospray ionization mass spectrometry (ESI-MS) in order to evidence the presence of these bioactive alkaloids.
Injection solutions for capillary electrophoresis and electrospray ionization mass spectrometry were prepared from stock solutions as described below.
With the Ultrasensitive Electrospray Ionization Mass Spectrometry Source and Interface, scientists from Pacific Northwest National Laboratory, Richland, Wash.
The second edition adds a chapter on electrospray ionization mass spectrometry.
The process uses broad-range polymerase chain reaction (PCR) to amplify nucleic acid targets from large groupings of organisms, electrospray ionization mass spectrometry for accurate mass measurements of PCR products, and base composition signature analysis to identify organisms in a sample.
During the last two decades there has been considerable growth in the development of electrospray ionization mass spectrometry (ESI-MS) as a practical method in the study of reaction mechanisms.
This approach has been applied to the analysis, for example, of transferrin isoform species performed with on-line immunoaffinity electrospray ionization mass spectrometry (4) for the biochemical diagnosis of another very challenging group of metabolic disorders, the congenital disorder of glycosylation (5).
Using electrospray ionization mass spectrometry, the base composition of each amplicon is determined and the combination of base compositions from multiple primer pairs is assembled to identify the organism in the sample.
Ultra-sensitive Electrospray Ionization Mass Spectrometry Source and Interface (Pacific Northwest National Laboratory)