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electroporation

   Also found in: Encyclopedia, Wikipedia, Hutchinson 0.01 sec.
electroporation
[-pôrā′shən]
a type of osmotic transfection in which an electric current is used to produce temporary holes in cell membranes, allowing the entry of nucleic acids or macromolecules (a way of introducing new deoxyribonucleic acid into the cell). See also transfection.
electroporation (i·lekˈ·trō·p·rāˑ·shn),
n technique by which cell membranes are made permeable by rapid pulses of high-voltage current. Has been used to treat cancers.
electroporation
the use of high-voltage electrical impulse to create pores through a cell membrane and allow uptake of DNA into a cell.


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Huang and his Pittsburgh colleague Feng Liu recently modified the electroporation process so that a metal syringe can double as the electrode.
Delivering the goods: gene therapy without the virus by Gorman, Jessica / Science News
Intramuscular delivery of DNA vaccines using Inovio's proprietary electroporation technology has been shown in primate studies to boost the immune response by orders of magnitude over DNA plasmid alone.
Inovio Biomedical DNA Delivery Technology Presented by Wyeth ... by Business Wire
By redesigning the environment in which electroporation occurs, he's been able to drop the current to one-thousandth of what had previously been needed.
Low-voltage gene transfer by J.R. / Science News
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