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eflornithine |
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eflornithine /ef·lor·ni·thine/ (DMFO) (ef-lor´nĭ-thēn″) an inhibitor of the enzyme catalyzing the decarboxylation of ornithine; used topically as the hydrochloride salt to reduce unwanted facial hair in females. eflornithine an antiprotozoal agent, used as the hydrochloride in trypanosomiasis and pneumocystiscarinii pneumonia. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Second-stage sleeping sickness (stage 2 HAT) was diagnosed, but treatment with eflornithine (obtained from the World Health Organization [WHO]) could not be initiated until 9 days after the diagnosis because of getting medication through customs. It's called eflornithine, but it's been in short supply because it had no other uses and the drug industry is infamous for not making drugs that can only be sold in Africa. Eflornithine is the only alternative drug to melarsoprol for patients in late-stage trypanosomiasis, generally defined by either the presence of trypanosomes in the CSF, a CSF leukocyte count higher than 5/[mm. |
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