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ectromelia
(redirected from Ectromelia virus)

   Also found in: Encyclopedia, Wikipedia 0.02 sec.
ectromelia /ec·tro·me·lia/ (ek″tro-me´le-ah) gross hypoplasia or aplasia of one or more long bones of one or more limbs.ectromel´ic
ec·tro·me·li·a (ktr-ml-, mly)
n.
Congenital absence of one or more limbs.

ectro·melic (-mlk, -mlk) adj.

ectromelia
[ek′trōmē′lyə]
Etymology: Gk, ektrosis + melos, limb
the congenital absence or incomplete development of the long bones of one or more of the limbs. Kinds of ectromelia are amelia, hemimelia, and phocomelia. ectromelic, adj., ectromelus, n.

ectromelia
1. gross hypoplasia or aplasia of one or more long bones of one or more limbs.
2. a generalized poxvirus disease of mice resembling smallpox in humans. Used in studies as a model of generalized virus infections.


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Today, technology allows genetic engineering of potentially devastating agents such as modified ectromelia virus (2), the weaponizing variola virus (former USSR) (3), the long distance dispersal of yellow fever-infested mosquitos (United States) (4), and the weaponizing of anthrax spores by many nations.
Ectromelia virus is closely related to human smallpox virus and causes a similar type of disease in mice (i.
Although the formation of typical A-type inclusions is restricted to cells infected with cowpox virus, ectromelia virus, and raccoonpox virus (2), the sequence coding the N-terminus of the protein is highly conserved in many viruses, including CPXV, VACV, variola virus, camelpox virus, and ectromelia virus.
 
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