econazole /econ·a·zole/ (ĕ-kon´ah-zōl) an imidazole derivative used as the nitrate salt as a broad-spectrum antifungal agent.
econazole
e·con·a·zole ( -k n  -z l )n. A broad-spectrum antifungal agent used in the treatment of athlete's foot and related fungal infections. |
econazole
[ikon′əzōl]
a topical antifungal agent.
indications It is prescribed in the treatment of tinea pedis, tinea cruris, tinea corporis, tinea versicolor, and candidiasis.
contraindication Known sensitivity to this drug prohibits its use.
adverse effects Among the most serious adverse effects are local irritation and hypersensitivity of the skin.
econazole
an imidazole antifungal agent related to miconazole; used topically as the nitrate in the treatment of fungal infections of the skin.
antifungal agent
Any substance which destroys or prevents the growth of fungi. It is one of the antibiotic groups. There are several classes of antifungal drugs: Polyenes, which cause an increase in fungal cell wall permeability leading to its death. Examples: amphotericin B, natamycin, nystatin. Azoles, which act either by inhibiting the synthesis of ergosterol, a component of fungal cell wall or by causing direct wall damage. Examples: clotrimazole, econazole, fluconazole, itraconazole, ketoconazole, miconazole. Pyrimidines, which interfere with the normal function of fungal cells. Example: flucytosine. Syn antimycotic agent.
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