Eadie-Hofstee plot | definition of Eadie-Hofstee plot by Medical dictionary
Ea·die-·Hof·stee plot (ē'de hahf'stē),
a graphic representation of enzyme kinetic data in which velocities, v, are plotted on the vertical axis as a function of the v:[S] ratio on the horizontal axis. On occasion, these axes are reversed. Sometimes referred to as the Eadie-Augustinsson plot or Woolf-Eadie-Augustinsson-Hofstee plot.
References in periodicals archive
However, a double reciprocal (Lineweaver-Burke) plot of these data resulted in nonlinear regresssion lines, which was confirmed by plotting the data in an Eadie-Hofstee plot.
Inhibition kinetics were retrieved from double reciprocal (Lineweaver-Burke) and Eadie-Hofstee plots.
However, Lineweaver-Burke and Eadie-Hofstee plots revealed that the analytic variation in the data from the treatments with higher inhibitor concentrations was too high to draw reliable conclusions about the type of inhibition.