ETS2

ETS2

A gene on chromosome  21q22.2 that encodes ETS2, a DNA-binding transcription factor that regulates numerous genes and is involved in stem cell development, cell senescence and death, and tumourigenesis.
References in periodicals archive ?
Next generation ETS2 will build on the success of ETS1 using cloud-based technology.
Using human choriocarcinoma (JEG-3 or JAR) cells, transcription factor AP-1 (official symbol, JUN) and ETS2 binding sites at the distal and proximal promoter regions, respectively, have been shown to be effective in IFNT-reporter transactivation (Ezashi et al.
In addition, the formation of a protein complex between CREBBP, JUN, and ETS2 is required for IFNT gene transcription (Xu et al.
With little miR-320 around, levels of a protein called ETS2 (pronounced Ets-two) rise in the fibroblast.
Finally, the abundance of ETS2 activates a number of genes that cause the fibroblast to secrete more than 50 factors that stimulate the proliferation and invasiveness of nearby cancer cells.
3B, the use of GAPDH-normalized ETS2 RNA and GAPDH-normalized uPA RNA as individual markers did not turn out to be informative.
Schwartz, PhD, director of Stem Cell Engineering at THI and director of UH's Center for Molecular Medicine and Experimental Therapeutics, used human skin cells called fibroblasts, and treated them with ETS2 and MESP1, two human genetic transcription factors that play important roles in the genetic network that produces cardiovascular tissues.
ETS2, a member of the ETS family of transcription factors, which have been proposed to have important functions in immune responses, cancer, and bone development, is located on chromosome 21 (21g22.
The ETS2 provides high-density DS1, DS3 and Fast Ethernet tributaries.
Carrier requests for a single, low-power, low-cost platform to efficiently provide services from DS1 up to OC-192 were the driving force behind White Rock's addition of its new ETS2 building block (which delivers DS1, Fast Ethernet and DS3 services in a single high-density tributary shelf).
Concur is partnering with some of the nation's largest TMCs, as well as a number of smaller TMCs, to serve the government through the ETS2 award.
The bookings strength is primarily a result of the better-than-expected momentum in our federal government ETS2 contract and continued strength in our commercial business.