ELF4

(redirected from ETS-related transcription factor Elf-4)

ELF4

A gene on chromosome Xq26 that encodes a transcriptional activator which binds and activates promoters of CSF2, IL3, IL8 and PRF1. ELF4 protein product is involved in natural killer cell development and function, innate immunity, and induction of cell cycle arrest in naïve CD8+ T cells. It is highly expressed in placenta and in various myeloid cell lines.