ELK3

(redirected from ETS domain-containing protein Elk-3)

ELK3

A gene on chromosome 12q23 that encodes a member of the ETS family of transcription factors and ternary complex factor (TCF) subfamily, which form a complex by binding to the serum response factor and serum response element in the c-fos proto-oncogene promoter. ELK3 is activated by signal-induced phosphorylation; it appears to inhibit transcription in absence of Ras, but activates it when Ras is present.
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