ERN1

ERN1

A gene on chromosome 17q24.2 that encodes the ubiquitously expressed endoplasmic reticulum (ER)-to-nucleus signalling 1 protein, which has intrinsic kinase and endoribonuclease activities and plays a key role in altering gene expression in response to endoplasmic reticulum-based stress signals. ERN1 senses unfolded proteins in the ER lumen, leading to enzyme auto-activation; the active endoribonuclease domain splices XBP1 mRNA, generating a new C-terminus and converting it into a potent unfolded-protein response transcriptional activator, triggering growth arrest and apoptosis.
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Objective 1: Construction of plant transformation binary vectors carrying the legume (Medicago truncatula) symbiosis-specific receptor kinases LYK3, NFP and SYMRK, and the transcription factors NSP1, NSP2, ERN1 and NIN driven by rice/constitutive promoters.
Objective 2: Development of the transgenic rice carrying the receptor protein LYK3, NFP and SYMRK, and the transcription factor NSP1, NSP2, ERN1 and NIN genes.
87 2,20 9,36 3,38 1938,85 848,47 3,34 ERN1 1,10 2,65 18,01 3,84 1466,31 778,35 4,67 ERN2 1,12 2,63 17,82 3,84 1470,29 785,90 4,66 ERN3 1,12 2,66 17,23 3,85 1468,78 780,94 4,69 Amostra Mg P[O.