HIV-1 gene

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HIV-1 gene

Any of the genes present in the human immunodeficiency virus. See AIDS.
HIV genes
art/trs gene rev gene, see there.
env gene Encodes viral coat proteins gp 120 and gp 41, which mediate CD4 binding and membrane fusion, controlled by tat and rev
gag gene Encodes nucleocapsid core proteins including p24
nef gene 3´ orf, B gene, ORF-2 gene Encodes a protein of unknown function found in infected Pts that may down-regulate viral expression–nef deletion results in a five-fold increase in viral DNA synthesis and replication
pol gene Encodes reverse transcriptase, protease, integrase and ribonuclease
R gene Encodes TAR–transcription activating response element, which has a nonspecific immunodeficiency effect
rev gene art/trs gene Encodes a 19 kD post-transcriptional protein regulator required for HIV replication, up-regulating HIV synthesis by transactivating anti-repression, ↑ levels of envelope RNA by regulating the env gene; inactivation of rev prevents viral replication–as measured by the successful production of the p24 glycoprotein by infected monocytes can be massively ↑ by adding cytokines to culture medium
tat gene Encodes a potent 14 kD transcription activator that amplifies HIV replication, the inactivation prevents viral replication
vif gene Facilitates infectivity of free HIV
vpr gene Encodes a weak transcription activator
vpu gene Unique to HIV-1, encodes a 16 kD product which, when mutated, has a 5-10-fold Ø in replicative capacity and is critical for efficient budding of virions NEJM 1991; 324:308rv
†Gene encoding regulatory protein
‡Gene encoding structural protein
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The eventual integration of Yodlee's software into ENV 2 will enable Finance Logix's goals-based financial planning tools, as well as other offerings on the Envestnet platform, to produce an even more powerful picture of every end client's financial health.
Since October 2000, over 700 ENV isolates have been typed in the Spanish Enterovirus Reference Laboratory, and only 1 imported EV13 isolate (data not shown) was detected in 2001 in a tourist from the Czech Republic who was visiting the Canary Islands.
However, they have been reported for other ENVs and some of them (sites I and III) are in the same position and have the same amino acids involved.
CBMG President Dr William Cao stated, "We are extremely proud to obtain ISO 9001:2008 and ENV certification, which are important milestones in the development of our company.
The ENV offers an exhilarating glimpse of the clean-and-green lifestyle that can be achieved through fuel cell technology," said Intelligent Energy CEO Harry Bradbury.
The pre-production prototype ENV currently has a top speed of 50 mph and can be used for up to four hours before needing hydrogen "refueling.
The result of the Intelligent Energy/Seymourpowell collaboration is the streamlined, lightweight ENV, which comes in two monochromatic colors: Black Supergloss and Iridescent White.
The ENV is light, fast and fun," said Seymourpowell Director Nick Talbot.
Public interest may also be heightened by another cutting-edge feature that differentiates the ENV from its counterparts: virtual silence.