elliptocytosis type 4

(redirected from EL4)

elliptocytosis type 4

A Rhesus-unlinked form (OMIM:109270) of hereditary elliptocytosis, a genetically heterogeneous, autosomal dominant haematologic disorder characterised by variable haemolytic anaemia and elliptical or oval red cells. 

Molecular pathology
Caused by defects of SLC4A1, which encodes a protein with an N-terminal 40-kDa domain located in the cytoplasm that acts as an attachment site for the red cell skeleton by binding ankyrin.
References in periodicals archive ?
The use of 5-azacytidine to establish constitutive interleukin 2-producing clones of the EL4 thymoma.
In this study we investigated the effects of alcohol fractions of the blood shell (blood ark shell), Scapharca broughtonii, on the production of IL-4 from mouse EL4 T cells.
KEY WORDS: Blood shell, Scapharca broughtonii, Interleukin-4, EL4 T cell, NF-AT
In this study we investigated the effects of alcohol fractions of the blood shell, Scapharca broughtonii, on the production of IL-4 from mouse EL4 T cells.
Cultures of EL4 thymoma cells were maintained in RPMI 1640 supplemented with 10% fetal bovine serum (GIBCO BRL, Grand Island, NY) and 1% penicillin/streptomycin at 37[degrees]C in a 5% C[O.
1987), was tested against the target VSV-N transfected EL4 (H-[2.
Citric acid-treated EL4 cells are recognized efficiently by VSV-N peptide-specific CTLs after PRN exposure.
To circumvent this problem, we replaced N1 cells as targets in the CTL lysis assay with untransfected EL4 cells plus titrated amounts of the target peptide VSV-N p52-59 (Figure 3).
The PRIMERGY BX630 is certified with all of the major server operating systems: Microsoft Windows Server 2003 Enterprise, Microsoft Windows Server 2003 Enterprise x64 Edition, Red Hat Linux EL4 x86/AMD64, Novell SUSE Linux ES-9 x86/AMD64, and VMware ESX Server 2.
System specifications Base system: HP DL380 G5, CPU: Intel Xeon 5160 (Woodcrest) x 2 @ 3GHz Memory: 14GB, Operating System: RedHat EL4 64 ClearSpeed Acceleration: Advance X620, CSXL 2.
The EL2 and EL4 models offer all of the smart battery management features in the slim-line package, and are equipped with two battery-powered outlets, a fax/modem surge suppressor, and a fault alarm when the battery is undercharged or overloaded.
The Pulsar EL4 is a 450VA/280W system offering backup for 3 minutes at full load or 8 minutes at half load.