EPHA5

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EPHA5

A gene on chromosome 4q13.1 that encodes a member of the ephrin-A receptor subfamily of receptor tyrosine kinases, which “promiscuously” bind membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signalling into neighbouring cells. EPNA5 is thought to constitute the cognate/functional ligand for EPHA5, acting as an axon guidance molecule during development. EPHA5 may be involved in the development of retinotectal, entorhino-hippocampal and hippocamposeptal pathways; with EFNA5 it also play a role in synaptic plasticity in adult brain by regulating synaptogenesis. In addition to its role in the nervous system, the EPHA5/EFNA5 interaction mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion.
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VIZpin allows users to install inexpensive ECKey EK7 Bluetooth readers then network them together via your smartphone.
In addition to the two East Kumkol wells drilled this year, one additional appraisal well, EK7, will be drilled for further delineation of the field.