CACNB4

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CACNB4

A gene on chromosome 2q22-q23 that encodes a beta subunit of a voltage-dependent calcium channel, which plays a regulatory role in calcium channel function by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling alpha-1 subunit membrane targeting.

Molecular pathology
CACNB4 mutations have been associated with idiopathic generalised epilepsy and juvenile myoclonic epilepsy.
References in periodicals archive ?
EJM boasts a diversified fleet of light mid-sized jets based all over the nation.
The chief visual, even kinetic, interest in EJM 1 -- EJM 2 is in Diller and Scofidio's enthralling manipulation of still and moving pictures.
We sold EJM the land and the plans for the building,'' said Jim Brown, vice president of real estate development for The Newhall Land and Farming Company.
The building EJM obtained through foreclosure is located in a stagnant real estate market where prices characteristically are depressed.
EJM has an estimated population of 120,000 people, a number which needs verification following recent displacements.
LATEST SCORES Championship, Division One Taunton: Somerset 358-6 (AN Petersen 136, JC Buttler 90 no, NRD Compton 52, ME Trescothick 51) lead Warwicks; Derby: Derbys 256 (S Chanderpaul 87 no; HF Gurney 4-86, SCJ Broad 4-57) trail Notts 325-5 (JWA Taylor 67 no, EJM Cowan 59, AD Hales 56); ; The Kia Oval: Surrey 351 (GC Wilson 124, VS Solanki 51; CJ Jordan 5-92) lead Sussex 204-2 (LWP Wells 108no).
Valerie Cushman is a partner in EJM, an interior design business in Biloxi, and a freelance writer.
Citing other key moves last year, the experts noted the purchase by Los Angeles-based EJM Development of the last remaining acreage of the McInnes Ranch in Oxnard.
The seven members elected are: Chairman of the Board Bruce Woodbury; Vice Chairman, President and CEO Patrick Wisman; Kirk Boylston of EJM Development; Ronald Britton of Rohill Operating Company; Robert Thornton; Charles Tierce; and Donald R.