EIF1AX

EIF1AX

A gene on chromosome Xp22.12 that encodes an essential translation initiation factor required for binding the 43S complex to the 5’ end of capped RNA. EIF1AX is required for the maximum rate of protein biosynthesis; it enhances ribosome dissociation into subunits and stabilises the binding of the initiator Met-tRNA(I) to 40S ribosomal subunits.
References in periodicals archive ?
5] Human genes: LPL, lipoprotein lipase; ZAP70, zeta-chain (ICR) associated protein kinase 70 kDa; PPIA, peptidylprolyl isomerase A (cyclophilin A); LMNB1, lamin B1; EIF1AX, eukaryotic translation initiation factor 1A, X-linked; CASC3, cancer susceptibility candidate 3; IGHV, immunoglobulin variable heavy chain region; PGKI, phosphoglycerate kinase 1; CD38, CD38 molecule.
We also tested 5 housekeeping genes [LMNB1, lamin B1; EIF1AX, eukaryotic translation initiation factor 1A, X-linked; CASC3 (also known as MLN51), cancer susceptibility candidate 3; PPIA; and PGK1, phosphoglycerate kinase 1] as endogenous controls (data not shown).