EFNB1

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EFNB1

A gene on chromosome Xq12 that encodes ephrin-B1, a cell surface GPI-bound ligand for the Eph family of tyrosine kinase receptors, which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. EFNB1 binds to receptor tyrosine kinases EPHB1 and EPHA1, and induces the collapse of commissural axons/growth cones; it may play a role in orienting longitudinally projecting axons. It interacts with GRIP1 and GRIP2.
 
Molecular pathology
Defects of EFNB1 cause craniofrontonasal syndrome.
References in periodicals archive ?
All the Chinese and English essays were assigned a code to facilitate their identification: NES is for native English speakers, NCS for native Chinese speakers, EFL1 for first-year EFL students, and EFL3 for third-year EFL students.
However, the difference between the NES and EFL3 texts ([X.
Evidently, the difference between the NES group and EFL1 group is broader than that between the NES group and EFL3 group.