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EDRF

   Also found in: Acronyms 0.01 sec.
EDRF,
abbreviation for endothelial-derived relaxing factor, a term which is now used synonymously with nitric oxide.

EDRF
endothelium-derived relaxing factor.


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Eight years later, he figured out that EDRF was in fact nitric oxide.
NO is known as the endothelium-derived relaxing factor, or EDRF, and a liable free radical with a half-life of about three to five seconds.
Nitric oxide is a biogenic messenger, an EDRF (15,16), and it activates the guanylyl cyclase system (17) [it converts guanosine triphosphate to cyclic guanosine monophosphate (cGMP)], raising the cGMP pool and therefore inducing, among other things, vasodilatation (17) by lowering the intracellular calcium ion (16).
 
 
 
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