EDAR


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Related to EDAR: Edgar, Sedar

EDAR

A gene on chromosome 2q13 that encodes ectodysplasin A receptor, a member of the tumour necrosis factor receptor family, which is a receptor for the soluble ligand ectodysplasin A. Once bound, EDAR activates the nuclear factor-kappaB, JNK and caspase-independent cell death pathways. EDAR is required for the development of hair, teeth and other ectodermally derived tissues.

Molecular pathology
EDAR mutations result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.
References in periodicals archive ?
PT Proton Edar Internasional Indonesia, a sole agent of Malaysia's car maker Proton in Indonesia said it will prepare six types of Proton cars to be disposed of in Indonesian market.
After being delayed for a year finally Malaysia's Proton Edar Sdn Bhd decided to assemble its Proton cars and sell them in Indonesian market starting April this year.
The provision of necessary services for the operation and maintenance of sanitation systems Granollers, La Garriga, Congost and EDAR CorrE d~Amunt.
Contract notice: Contract, the open, for maintenance and improvement of existing green areas in the "zone e ~which includes the following facilities: edar algete, edar casaquemada, edar arroyo de la vega and its surroundings.